• Med Princ Pract · Jan 2021

    Randomized Controlled Trial

    Nasal Polyposis and Its Association with Cardiac Functions.

    • Sapna Dhiman, Abhishek Dhiman, Ramesh K Azad, Prakash C Negi, Bhushan Lal, and Jagdeep S Thakur.
    • Department of Otolaryngology-Head & Neck Surgery (ENT), Indira Gandhi Medical College, Shimla, India.
    • Med Princ Pract. 2021 Jan 1; 30 (6): 522-526.

    ObjectiveThe aim of the study was to ascertain the effect of nasal polyposis on cardiac functions.Material And MethodsA prospective randomized interventional open-label endpoint-controlled study was conducted in an academic tertiary care hospital. Thirty-one patients with chronic rhinosinusitis with nasal polyposis were enrolled and administered fluticasone furoate nasal spray for 3 weeks before randomly segregation into surgical or medical group. The treatment continued for 3 months in both groups. The SNOT-22 (Sino-Nasal Outcome Test-22) score, polyp grade, and right ventricular and pulmonary arterial functions were recorded in both groups before and after 3 months of the intervention.ResultsBoth groups had significant improvement in SNOT-22 scores after 3 months of intervention. Both groups showed improvement in cardiac functions, but statistical significance was found only in subjects who underwent surgery.ConclusionNasal polyp affects cardiac functions, and this needs further evaluation and research through studies on large samples.© 2021 The Author(s). Published by S. Karger AG, Basel.

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