• Demetrio Ortega Rumi, Maria Cecília Solimene, Júlio Yoshio Takada, César José Grupi, Dante Marcelo Giorgi, Sérgio Paulo Rigonatti, Protásio Lemos da Luz, and José Antonio Franchini Ramires.
• Instituto de Psiquiatria do Hospital das Clinicas da FMUSP, Sao Paulo, Brazil.
• Arq. Bras. Cardiol. 2002 Aug 1; 79 (2): 149-60.

ObjectiveTo study cardiovascular alterations in young patients with no apparent organic disease who underwent electroconvulsive therapy.MethodsThe study comprised 47 healthy patients (22 males and 25 females) with a mean age of 30.3 years, who underwent electroconvulsive therapy. Ambulatory blood pressure monitoring and continuous electrocardiographic monitoring (Holter monitor) were performed during 24 hours. Blood pressure and heart rate were assessed 4 hours prior to electric shock administration, during electric shock administration, and 3 hours after electric shock administration. Arrhythmias and alterations in the ST segment in 24 hours were recorded.ResultsOn electroconvulsive therapy, a significant increase in blood pressure and heart rate was observed and the measurements returned to basal values after 25 minutes. Three females had tracings with depression of the ST segment suggesting myocardial ischemia prior to and after electroconvulsive therapy. Coronary angiography was normal. No severe cardiac arrhythmias were diagnosed.Conclusion1) Electroconvulsive therapy is a safe therapeutic modality in psychiatry; 2) it causes a significant increase in blood pressure and heart rate; 3) it may be associated with myocardial ischemia in the absence of coronary obstructive disease; 4) electroconvulsive therapy was not associated with the occurrence of severe cardiac arrhythmias.

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