• Clinical nuclear medicine · Mar 2016

    Case Reports

    "Cold" Spondylodiscitis on 18F-FDG PET/CT in a Patient With Myelofibrosis.

    • Etienne Rousseau and Khun Visith Keu.
    • From the Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, Quebec, Canada.
    • Clin Nucl Med. 2016 Mar 1; 41 (3): e156-8.

    AbstractA 74-year-old man was evaluated by bone scan for possible rib fractures, which revealed a diffuse skeletal uptake secondary to myelofibrosis and focal midthoracic uptake. Chest CT and F-FDG PET/CT demonstrated pathological vertebral fractures of the midthoracic spine, which appeared as a cold defect on PET comparing to intense marrow uptake related to myelofibrosis and a lung nodule with a low uptake, later biopsy-proven as non-small cell lung carcinoma (NSCLC). MRI confirmed CT findings for the spine noting also an enhanced epidural collection. Biopsies did not reveal malignant cells. Final diagnosis was spondylodiscitis and a stage I NSCLC.

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