• Contemp Clin Trials · Jul 2021

    Moving forward in clinical research with master protocols.

    • Jay J H Park, Louis Dron, and Edward J Mills.
    • Experimental Medicine, Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada. Electronic address: jayhpark1@alumni.ubc.ca.
    • Contemp Clin Trials. 2021 Jul 1; 106: 106438.

    AbstractWith billions of dollars in research and development (R&D) funding continuing to be invested, the novel coronavirus disease 2019 (COVID-19) has become into a singular focus for the scientific community. However, the collective response from the scientific communities have seen poor return on investment, particularly for therapeutic research for COVID-19, revealing the existing weaknesses and inefficiencies of the clinical trial enterprise. In this article, we argue for the importance of structural changes to existing research programs for clinical trials in light of the lessons learned from COVID-19.Copyright © 2021 Elsevier Inc. All rights reserved.

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