• World Neurosurg · Oct 2021

    Hemangioblastoma of the peripheral nervous system: a critical analysis of its rarity.

    • Nikhil K Murthy, Russell R Lonser, and Robert J Spinner.
    • Department of Neurosurgery, Mayo Clinic, Rochester, Minnesota, USA.
    • World Neurosurg. 2021 Oct 1; 154: e707-e709.

    AbstractVon Hippel-Lindau (VHL) disease is a multisystem disease cause by germline mutations of the VHL tumor suppressor gene. Hemangioblastomas are the most common manifestation of VHL disease and can occur in the central nervous system in up to 90% of these patients. By contrast, we found only one true case of a peripheral nervous system (PNS) hemangioblastoma in the setting of VHL. We explore the possible reasons behind the lack of PNS hemangioblastomas in VHL disease.Copyright © 2021 Elsevier Inc. All rights reserved.

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