Heyde syndrome--the link between aortic stenosis and

Rev Port Cardiol · Feb 2010

Case Reports

Heyde syndrome--the link between aortic stenosis and gastrointestinal bleeding.

Aortic valve stenosis can be complicated by gastrointestinal bleeding from angiodysplasia. A deficiency of high molecular weight multimers of von Willebrand factor (vWF) (type 2A von Willebrand disease) provides the link between this association, which is known as Heyde syndrome. Aortic valve replacement corrects the vWF abnormalities with long-term resolution of gastrointestinal bleeding. The authors present a case report and a review of this association.

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- Alexandra Vaz, Andreia Correia, Borges Martins, Joana Capelo, Pedro Ferreira, Pedro Henriques, and Oliveira Santos.
- Serviço de Medicina I, Hospital S. Teotónio, Viseu, Portugal. xana.vaz29@gmail.com
- Rev Port Cardiol. 2010 Feb 1; 29 (2): 309-14.
AbstractAortic valve stenosis can be complicated by gastrointestinal bleeding from angiodysplasia. A deficiency of high molecular weight multimers of von Willebrand factor (vWF) (type 2A von Willebrand disease) provides the link between this association, which is known as Heyde syndrome. Aortic valve replacement corrects the vWF abnormalities with long-term resolution of gastrointestinal bleeding. The authors present a case report and a review of this association.

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Heyde syndrome--the link between aortic stenosis and gastrointestinal bleeding.

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