• Adv Respir Med · Jan 2019

    Does bronchiectasis affect COPD comorbidities?

    • Adam Nowiński, Damian Korzybski, Michał Bednarek, Anna Goljan-Geremek, Elżbieta Puścińska, and Paweł Śliwiński.
    • Second Department of Respiratory Medicine, Institute of Tuberculosis and Lung Diseases, Warsaw, Poland. a.nowinski@igichp.edu.pl.
    • Adv Respir Med. 2019 Jan 1; 87 (6): 214-220.

    IntroductionCOPD and bronchiectasis, chronic inflammation disorders of the bronchial tree through the mechanism of 'spill-over' of inflammatory mediators, may lead to systemic manifestations of illness of the respiratory system and comorbidities. The aim of the study was to evaluate the frequency of coexisting chronic obstructive pulmonary disease and bronchiectasis and influence of bronchiectasis on COPD comorbid diseases.Material And MethodsA post-hoc cross-sectional analysis of cohort study of 288 consecutive patients hospitalized due to acute exacerbation of COPD was performed.Results177 males (61.5%) and 111 females (38.5%) with mean age = 71.0 8 ± 8.9 yrs, FEV1 % pred. = 34.6 ± 16.8 with COPD diagnosis were studied. In this group, 29 (10.1%) patients presented with bronchiectasis confirmed by HRCT scan. COPD patients with and without bronchiectasis had similar Charlson index results (2.5 vs 2.1, p=0.05). COPD patients with bronchiectasis required longer hospitalization during exacerbation. COPD patients with bronchiectasis significantly more often than patients without this comorbidity revealed the features of colonization with P. aeruginosa (OR = 4.17, p = 0.02).ConclusionsBronchiectasis is a relatively common comorbidity in COPD patients. COPD patients with bronchiectasis are more frequently colonized with P. aruginosa comparing to non-bronchiectasis COPD patients. We did not confirm the influence of bronchiectasis on COPD comorbidities.

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