-
- D Levêque, J Wihlm, and F Jehl.
- Laboratoire de pharmacocinétique, Institut de Bactériologie, Strasbourg, France.
- Bull Cancer. 1996 Mar 1; 83 (3): 176-86.
AbstractCatharanthus alkaloids are antitumoral drugs widely used in the treatment of malignant diseases. This review summarizes different aspects of their pharmacology (mechanism of action, resistance, clinical pharmacokinetics) as well as information on their uses in the clinical setting.
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