• Head & neck · Nov 2020

    Salivary and lacrimal dysfunction after radioactive iodine for differentiated thyroid cancer: American Head and Neck Society Endocrine Surgery Section and Salivary Gland Section joint multidisciplinary clinical consensus statement of otolaryngology, ophthalmology, nuclear medicine and endocrinology.

    • Michael C Singer, Francis Marchal, Peter Angelos, Vic Bernet, Laura Boucai, Samanta Buchholzer, Brian Burkey, David Eisele, Evren Erkul, Frederic Faure, Suzanne K Freitag, Marion Boyd Gillespie, Richard Mack Harrell, Dana Hartl, Megan Haymart, Jonathan Leffert, Susan Mandel, Barbra S Miller, John Morris, Elizabeth N Pearce, Rahmatullah Rahmati, William R Ryan, Barry Schaitkin, Martin Schlumberger, Brendan C Stack, Doug Van Nostrand, Ka Kit Wong, and Gregory Randolph.
    • Department of Otolaryngology - Head and Neck Surgery, Henry Ford Health System, Detroit, Michigan, USA.
    • Head Neck. 2020 Nov 1; 42 (11): 3446-3459.

    BackgroundPostoperative radioactive iodine (RAI) administration is widely utilized in patients with differentiated thyroid cancer. While beneficial in select patients, it is critical to recognize the potential negative sequelae of this treatment. The prevention, diagnosis, and management of the salivary and lacrimal complications of RAI exposure are addressed in this consensus statement.MethodsA multidisciplinary panel of experts was convened under the auspices of the American Head and Neck Society Endocrine Surgery and Salivary Gland Sections. Following a comprehensive literature review to assess the current best evidence, this group developed six relevant consensus recommendations.ResultsConsensus recommendations on RAI were made in the areas of patient assessment, optimal utilization, complication prevention, and complication management.ConclusionSalivary and lacrimal complications secondary to RAI exposure are common and need to be weighed when considering its use. The recommendations included in this statement provide direction for approaches to minimize and manage these complications.© 2020 Wiley Periodicals LLC.

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