• J Foot Ankle Surg · Mar 2017

    Propensity Score Matching: Retrospective Randomization?

    • Daniel C Jupiter.
    • Assistant Professor, Department of Preventive Medicine and Community Health, The University of Texas Medical Branch, Galveston, TX. Electronic address: dajupite@utmb.edu.
    • J Foot Ankle Surg. 2017 Mar 1; 56 (2): 417-420.

    AbstractRandomized controlled trials are viewed as the optimal study design. In this commentary, we explore the strength of this design and its complexity. We also discuss some situations in which these trials are not possible, or not ethical, or not economical. In such situations, specifically, in retrospective studies, we should make every effort to recapitulate the rigor and strength of the randomized trial. However, we could be faced with an inherent indication bias in such a setting. Thus, we consider the tools available to address that bias. Specifically, we examine matching and introduce and explore a new tool: propensity score matching. This tool allows us to group subjects according to their propensity to be in a particular treatment group and, in so doing, to account for the indication bias.Copyright © 2017 American College of Foot and Ankle Surgeons. Published by Elsevier Inc. All rights reserved.

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