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J Oncol Pharm Pract · Mar 2010
The role of the pharmacist in optimizing the use of erythropoietin stimulating agents.
- GebaraShereen NabhaniSNSchool of Pharmacy and Chemistry, Kingston University, Penrhyn Road, Kingston upon Thames KT1 2EE, UK. s.nabhani@kingston.ac.uk and Hiba Moubayed.
- School of Pharmacy and Chemistry, Kingston University, Penrhyn Road, Kingston upon Thames KT1 2EE, UK. s.nabhani@kingston.ac.uk
- J Oncol Pharm Pract. 2010 Mar 1; 16 (1): 33-7.
PurposeWith the emerging new warnings surrounding the use of erythropoiesis-stimulating agents (ESAs), the pharmacist's role as health educator and risk communicator expands further to include patient scrutiny to check for eligibility and patient monitoring to check for response or toxicity. This review explores the benefits and risks linked to ESAs use, and the proposed role.SummaryESAs have been increasingly used for the treatment of chemotherapy-induced anemia because of its documented effect on decreasing transfusion dependency. However, their use has been associated with thromboembolic complications, tumor progression, and decreased overall survival. This review covers current recommendations and guidelines that surround ESAs use in the supportive care of cancer patients.ConclusionTo minimize or prevent the complications associated with ESAs use, cancer patients should be adequately monitored and counseled. This highlights the importance of the pharmacist's involvement to optimize patient care.
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