• Ian D Coulter, Patricia M Herman, Gery W Ryan, Ronald D Hays, Lara G Hilton, and Margaret D Whitley.
• RAND Corporation, University of California Los Angeles, Southern California Health Sciences, Santa Monica, California. Electronic address: coulter@rand.org.
• J Manipulative Physiol Ther. 2018 Nov 1; 41 (9): 800-806.

ObjectivesThe purpose of this article is to report on the Center of Excellence for Research on Complementary and Alternative Medicine at RAND Corporation. The overall project examined the appropriateness of chiropractic spinal manipulation and mobilization for chronic low back pain and chronic cervical pain using the RAND and University of California Los Angeles Appropriateness Method, including patient preferences and costs, to acknowledge the importance of patient-centered care in clinical decision-making.MethodsThis article is a narrative summary of the overall project and its inter-related components (ie, 4 Research Project Grants and 2 centers), including the Data Collection Core, whose activities and learning will be the subject of a following series of methods articles.ResultsThe project team faced many challenges in accomplishing data collection goals. The processes we developed to overcome barriers may be of use to other researchers and for practitioners who may want to participate in such studies in complementary and integrative health, which previously was known as complementary and alternative medicine.ConclusionFor this large, complex, successful project, we gathered online survey data, collected charts, and abstracted chart data from thousands of chiropractic patients. The present article delineates the challenges and lessons that were learned during this project so that others may gain from the authors' experience. This information may be of use to future research that collects data from independent practitioners and their patients because it provides what is needed to be successful in such studies and may encourage participation.Copyright © 2018. Published by Elsevier Inc.

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