• Alzheimers Dement · Jan 2008

    Review

    Drug discovery and the prevention of Alzheimer's disease.

    • Howard Fillit.
    • Executive Director, The Alzheimer's Drug Discovery Foundation, New York, NY, USA. hfillit@alzdiscovery.org
    • Alzheimers Dement. 2008 Jan 1; 4 (1 Suppl 1): S26-8.

    AbstractProgress in understanding the pathogenesis of Alzheimer's disease (AD) has advanced rapidly and has achieved parity in knowledge with other chronic degenerative diseases of the elderly. This knowledge has not yet been successfully translated into new and effective disease-modifying drugs. Many new clinical candidates are currently in clinical trials, and it is likely that some will be successful in achieving regulatory approval. Nevertheless, primary prevention of AD remains the ultimate and most important goal of research efforts because the unique clinical features of this dementing disease create a number of challenges for drug development, regulatory approval, and payment. Ultimately, the development of truly effective disease-modifying drugs through accelerated drug discovery is the only real pathway to primary prevention.

      Pubmed     Full text   Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…