• Chunyan Nie, Tianzhu Li, and Xiaoxia Guo.
• 1 Department of Geriatrics, The Fourth Affiliated Hospital of Harbin Medical University, Harbin, China.
• West J Nurs Res. 2019 Sep 1; 41 (9): 1254-1269.

AbstractThe objective of this article is to investigate the effects of intensive patients' education and lifestyle improving program (IPEL) on anxiety, depression, and overall survival (OS) in coronary artery disease (CAD) patients with anxiety and depression. In all, 224 CAD patients with anxiety and depression were randomly assigned to IPEL or control group. In Stage I, the IPEL group received IPEL and usual care, while the control group only received usual care. In Stage II, patients were further followed up and OS analysis was performed. Hospital Anxiety and Depression Scale-anxiety (HADS-A) and HADS-depression (HADS-D) were used to assess anxiety and depression. IPEL reduced HADS-A score at Month 9 (M9)/M12, and the percentage of anxiety at M12 and HADS-A score changed. IPEL reduced HADS-D score at M12, and the percentage of depression at M12 and HADS-D score changed compared with control. Patients with nonanxiety/nondepression at M12 in the IPEL group showed better OS. IPEL reduces anxiety and depression and improves OS in CAD patients.

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