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Oncology nursing forum · May 1994
Review Case ReportsLambert-Eaton myasthenic syndrome in small cell lung cancer: nursing implications.
- C S Struthers.
- Glenbrook Hospital, Glenview, IL.
- Oncol Nurs Forum. 1994 May 1; 21 (4): 677-83; quiz 684-5.
PurposeTo describe the pathophysiology and nursing care of patients with Lambert-Eaton myasthenic syndrome (LEMS), a little-known paraneoplastic syndrome.Data SourcesPublished articles, books and book chapters, and clinical trial experience.Data SynthesisLEMS most commonly is associated with small cell lung cancer. Clinical presentation is characterized by weakness of the proximal muscles of the pelvis, thighs, shoulders, and arms and a weakening or absence of deep tendon reflexes. These symptoms are the manifestations of an abnormality at the neuromuscular junction and may precede the diagnosis of lung cancer.ConclusionsThe oncology nurse knowledgeable about the pathophysiology, clinical features, diagnostic evidence, and treatment of LEMS is better able to care for and teach patients with this disorder.Nursing ImplicationsNurses must assist patients in adjusting not only to a diagnosis of cancer and its treatment effects but also to the symptoms of LEMS, including impaired mobility, self-care deficits, and fatigue.
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