Bicuspid aortic valve aortopathy in adults: Incidence,

Int. J. Cardiol. · Dec 2015

Review

Bicuspid aortic valve aortopathy in adults: Incidence, etiology, and clinical significance.

Bicuspid aortic valve is the most common congenital heart defect and is associated with an aortopathy manifested by dilatation of the ascending thoracic aorta. The clinical consequences of this aortopathy are the need for periodic monitoring of aortic diameters, elective prophylactic surgical aortic repair, and the occurrence of aortic dissection or rupture. This review describes the current knowledge of BAV aortopathy in adults, including incidence, pathophysiologic insights into its etiology, contemporary hypothesis-generating observations into its complications, and recommendations for monitoring and intervention.

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- Hector I Michelena, Alessandro Della Corte, Siddharth K Prakash, Dianna M Milewicz, Artur Evangelista, and Maurice Enriquez-Sarano.
- Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, USA. Electronic address: michelena.hector@mayo.edu.
- Int. J. Cardiol. 2015 Dec 15; 201: 400-7.
AbstractBicuspid aortic valve is the most common congenital heart defect and is associated with an aortopathy manifested by dilatation of the ascending thoracic aorta. The clinical consequences of this aortopathy are the need for periodic monitoring of aortic diameters, elective prophylactic surgical aortic repair, and the occurrence of aortic dissection or rupture. This review describes the current knowledge of BAV aortopathy in adults, including incidence, pathophysiologic insights into its etiology, contemporary hypothesis-generating observations into its complications, and recommendations for monitoring and intervention. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

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Bicuspid aortic valve aortopathy in adults: Incidence, etiology, and clinical significance.

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