• Internal medicine · Feb 2022

    Case Reports

    Left Hemiplegia Possibly Due to Glucose Reperfusion Injury after Recovery of Severe Hypoglycemia in a Woman with Type 2 Diabetes Mellitus.

    • Erika Sugito, Tetsuro Tsujimoto, Noritoshi Arai, Ryotaro Bouchi, Mitsuru Ohsugi, Akiyo Tanabe, Kohjiro Ueki, and Hiroshi Kajio.
    • Department of Diabetes, Endocrinology, and Metabolism, Center Hospital, National Center for Global Health and Medicine, Japan.
    • Intern. Med. 2022 Feb 15; 61 (4): 513-516.

    AbstractA 79-year-old woman with type 2 diabetes receiving insulin was rushed to our hospital due to severe hypoglycemia. Glucose was administered, and the consciousness disturbance was promptly improved. A few hours later, conjugate deviation of the eyes to the right and left hemiplegia occurred at a normal glucose level. Cerebral magnetic resonance imaging (MRI) showed hyperintensities of the right posterior limb of the internal capsule and the medial thalamus on diffusion-weighted imaging sequences. However, the changes observed using MRI disappeared completely on the third day, and her symptoms subsequently improved. This may have been a case of glucose reperfusion injury.

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