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Case Reports
An Autopsy Case of Disseminated Varicella Zoster Virus Infection During the Treatment of Nephrotic Syndrome.
- Katsuhisa Kuwano, Yuki Ota, Kiyokazu Tsuji, Kenta Torigoe, Ayuko Yamashita, Kumiko Muta, Mineaki Kitamura, Hiroshi Yamashita, Tadashi Uramatsu, Masato Tashiro, Hiroko Hayashi, Koichi Izumikawa, Hiroshi Mukae, and Tomoya Nishino.
- Department of Nephrology, Nagasaki University Hospital, Japan.
- Intern. Med. 2022 Feb 15; 61 (4): 571-576.
AbstractA 68-year-old woman developed systemic blisters while receiving treatment for nephrotic syndrome. As she also developed marked liver dysfunction and disseminated intravascular coagulation, she was admitted to our hospital. She was diagnosed with varicella zoster virus (VZV) infection. Treatment was administered in the intensive-care unit, but the patient died on day 24 post-admission after severe VZV infection. A post-mortem examination showed micro-abscesses and necrosis caused by varicella zoster infection in multiple organs, including the liver, kidneys, and gastrointestinal tract. Because VZV infection can become severe in immunocompromised patients, careful consideration is needed for the prevention and treatment of the viral infection.
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