• Internal medicine · Feb 2022

    Case Reports

    Hemodynamic Collapse Caused by Cardiac Dysfunction and Abdominal Compartment Syndrome in a Patient with Mitochondrial Disease.

    • Reiko Shiomura, Shuhei Tara, Nobuaki Ito, Makoto Watanabe, Toshiki Arai, Noriyuki Kobayashi, Masaki Wakita, Yuhi Fujimoto, Junya Matsuda, Jun Nakata, Takeshi Yamamoto, and Wataru Shimizu.
    • Division of Cardiovascular Intensive Care, Nippon Medical School, Japan.
    • Intern. Med. 2022 Feb 15; 61 (4): 489-493.

    AbstractWe herein report a case of mitochondrial disease with heart and intestinal tract involvement resulting in hemodynamic collapse. A 66-year-old woman was transferred to our hospital because of cardiogenic shock. Vasopressors were administered, and a circulatory support device was deployed. However, her hemodynamics did not improve sufficiently, and we detected abdominal compartment syndrome caused by the aggravation of chronic intestinal pseudo-obstruction as a complication. Insertion of a colorectal tube immediately decreased the intra-abdominal pressure, improving the hemodynamics. Finally, we diagnosed her with mitochondrial disease, concluding that the resulting combination of acute heart failure and abdominal compartment syndrome had aggravated the hemodynamics.

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