• Climério Pereira Nascimento Junior, Sergio Samir Arap, Melani Ribeiro Custodio, Ledo Mazzei Massoni Neto, Marília D'Elboux Guimarães Brescia, Rosa Maria Affonso Moyses, Vanda Jorgetti, and Fabio Luiz de Menezes Montenegro.
• Universidade de São Paulo, Serviço de Cirurgia de Cabeça e Pescoço - São Paulo (SP), Brasil.
• Rev Assoc Med Bras (1992). 2021 Feb 1; 67 (2): 230-234.

ObjectiveThe parathormone level after parathyroidectomy in dialysis patients are of interest. Low levels may require cryopreserved tissue implantation; however, the resection is necessary in case of recurrence. We analyzed post parathyroidectomy parathormone levels in renal hyperparathyroidism.MethodsProspective observation of postoperative parathormone levels over defined periods in a cohort of dialysis patients that underwent total parathyroidectomy and immediate forearm autograft from 2008 to 2010, at a single tertiary care hospital.ResultsOf 33 patients, parathormone levels until 36 months could be divided into four patterns. Patients with stable function (Pattern 1) show relatively constant levels after two months (67% of the cases). Early function and later failure (Pattern 2) were an initial function with marked parathormone reduction before one year (18%). Graft recurrence (Pattern 3) showed a progressive increase of parathormone in four cases (12%). Complete graft failure (Pattern 4) was a nonfunctioning implant at any period, which was observed in one patient (3%). Parathormone levels of Pattern 3 became statistically different of Pattern 1 at 36 months.ConclusionsPatients that underwent the total parathyroidectomy and autograft present four different graft function patterns with a possible varied therapeutic management.

14 keywords...

hide…