• Laura Escolà-Vergé, Blanca Borràs-Bermejo, Ibai Los-Arcos, Juliana Esperalba, Carmen Ferrer, and Nuria Fernández-Hidalgo.
• Servicio de Enfermedades Infecciosas, Hospital Universitari Vall d'Hebron, Barcelona, España; Red Española para la Investigación en Enfermedades Infecciosas (REIPI RD16/0016/0003), Instituto de Salud Carlos III, Madrid, España. Electronic address: lauraescola@gmail.com.
• Med Clin (Barc). 2022 Aug 12; 159 (3): 134-136.

Background And ObjectiveThe objective was to describe the clinical characteristics and prognosis of patients with nosocomial SARS-CoV-2 infection.MethodsAn observational and prospective study was performed in a referral hospital. We included all adult patients diagnosed with nosocomial SARS-CoV-2 infection in October 2020. Nosocomial infection was defined as a negative PCR for SARS-CoV-2 on admission and a positive PCR after 7 days of hospitalization.ResultsWe included 66 cases of nosocomial SARS-CoV-2 infection: 39 (59%) men, median age at diagnosis was 74.5 years (IQR 56.8-83.1) and median Charlson comorbidity index was 3 points (IQR 1-5). Twenty-seven (41%) developed pneumonia and 13 (20%) died during admission. Mortality at 28 days was 33% (22 patients). Mortality at 28 days in the 242 patients with community-acquired SARS-CoV-2 infection who were hospitalized during the same period was 10%.ConclusionsPreventive measures and early detection of nosocomial outbreaks of COVID-19 should be prioritized to minimize the negative impact of this infection.Copyright © 2021 Elsevier España, S.L.U. All rights reserved.

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