• Healthc (Amst) · Sep 2016

    Trials without tribulations: Minimizing the burden of pragmatic research on healthcare systems.

    • Eric B Larson, Chris Tachibana, Ella Thompson, Gloria D Coronado, Lynn DeBar, Laura M Dember, Stacey Honda, Susan S Huang, Jeffrey G Jarvik, Christine Nelson, Edward Septimus, Greg Simon, and Karin E Johnson.
    • Group Health Research Institute, Seattle, WA, USA.
    • Healthc (Amst). 2016 Sep 1; 4 (3): 138-41.

    AbstractPragmatic clinical trials are increasingly common because they have the potential to yield findings that are directly translatable to real-world healthcare settings. Pragmatic clinical trials need to integrate research into clinical workflow without placing an undue burden on the delivery system. This requires a research partnership between investigators and healthcare system representatives. This paper, organized as a series of case studies drawn from our experience in the NIH Health Care Systems Research Collaboratory, presents guidance from informational interviews of physician-scientists, health services researchers, and delivery system leaders who recently launched pragmatic clinical trials. Copyright © 2015 Elsevier Inc. All rights reserved.

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