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- Philippe Calain, Jean-Paul Chaine, Eliaser Johnson, Mary-Lou Hawley, Michael J O'Leary, Hitoshi Oshitani, and Claire-Lise Chaignat.
- WHO Western Pacific Regional Office, Manila, Philippines.
- Vaccine. 2004 Jun 23; 22 (19): 2444-51.
AbstractControl measures to limit the spread of a cholera outbreak in Pohnpei Island (Micronesia), included mass vaccination with the single-dose live-attenuated oral cholera vaccine CVD 103-HgR as a potential adjunct measure. The outbreak provided a unique opportunity to evaluate the practicality of use and effectiveness of this vaccine. Under field conditions encountered in Pohnpei, crude vaccine efficacy was estimated at 79.2% (95% CI: 71.9-84.6%) in the target population. Retrospective analysis suggests that mass vaccination with oral cholera vaccines can be a useful adjunct tool for controlling outbreaks, particularly if implemented early in association with other standard control measures.
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