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Pacing Clin Electrophysiol · Mar 2004
Pacemaker and implantable cardioverter defibrillator implantation without reversal of warfarin therapy.
- Michael C Giudici, Deborah L Paul, Praveen Bontu, and S Serge Barold.
- Division of Cardiology, Genesis Medical Center, Davenport, Iowa 52803, USA. giudici@cvmedpc.com
- Pacing Clin Electrophysiol. 2004 Mar 1; 27 (3): 358-60.
AbstractThe study evaluated all patients undergoing permanent pacemaker and ICD implantation over a 4-year period to determine if anticoagulated patients required normalization of coagulation factors in the periprocedural period. The study included 1,025 (597 men, 428 women, age 24-100 years, mean 72 years) consecutive patients who underwent device implantation using mostly a percutaneous subclavian approach. The procedures were performed without reversal of anticoagulation in 470 patients with INRs >or= 1.5 at the time of the procedure (mean INR 2.6 +/- 1.0, range 1.5-7.5). The complication rate in the anticoagulated group was similar to those in patients with a normal INR. Routine normalization of coagulation factors prior to pacemaker/ICD placement may not be necessary.
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