• Eva García-Fontán, Montserrat Blanco Ramos, Jose Soro García, Rommel Carrasco, Miguel Ángel Cañizares, and Ana González Piñeiro.
• Thoracic Surgery Department, Alvaro Cunqueiro University Clinical Hospital, EOXI, Vigo, Spain.
• Med Clin (Barc). 2019 Feb 1; 152 (3): 104-106.

IntroductionDiffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH) is a rare disorder characterized by a proliferation of neuroendocrine cells within the lung. It is classically described as a disease with persistent cough, dyspnea and wheezing in non-smoker middle aged females. CT of the chest reveals diffuse air trapping with mosaic pattern.Patients And MethodsWe present two cases of DIPNECH that were sent to our department to perform a lung biopsy with the diagnostic suspicion of diffuse interstitial disease. Both cases were women with a history of chronic cough and moderate effort dyspnea.Results And DiscussionThe aim of this paper is that physicians take into account this diagnostic entity before treating as an asthmatic a patient with these characteristics, not forgetting that they are prenoplastic lesions.Copyright © 2018 Elsevier España, S.L.U. All rights reserved.

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