• J Fla Med Assoc · Dec 1990

    Conservative surgery and radiation therapy for early stage breast cancer. Can large trial experiences be reproduced in a community hospital setting?

    • A A Lewin, A A Abitbol, J G Schwade, D Osman, R DerHagopian, J Ostroski, C Serago, P Houdek, and J Bujnoski.
    • Baptist Hospital of Miami, Regional Cancer Treatment Center 33256.
    • J Fla Med Assoc. 1990 Dec 1; 77 (12): 1034-6.

    AbstractConservative surgery and radiation therapy were used to treat 212 patients with AJC clinical Stage I or II breast carcinoma at the Baptist Hospital of Miami. All had lumpectomy and most axillary lymph node dissection, followed by breast irradiation to a dose of 45 Gy and a boost dose of 14 to 16 Gy to the surgical bed. Median follow-up was 55 months. The five-year actuarial local control and survival rates were 94% and 86% respectively. Eighty-six percent of the patients had excellent or good cosmetic results with minimal differences between the treated and untreated breasts. Treatment-related complications were minor and infrequent. These results appear comparable to retrospective reviews at major university centers and ongoing prospective randomized trials.

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