• Otolaryngol. Clin. North Am. · Dec 2017

    Review

    Immunotherapy: Treating with Fewer Allergens?

    • Cecelia Damask.
    • Private Practice, Florida Hospital Altamonte Springs, 795 Primera Boulevard Suite 1031, Lake Mary, FL 32746, USA; University of Central Florida College of Medicine, 6850 Lake Nona Boulevard, Orlando, FL 32827, USA. Electronic address: cbaukus@yahoo.com.
    • Otolaryngol. Clin. North Am. 2017 Dec 1; 50 (6): 1153-1165.

    AbstractPolysensitization, sensitization to more than one allergen, is a common feature of patients with allergic rhinitis, and may be a risk factor for subsequent development of allergic diseases, especially allergic asthma. However, a polysensitized patient does not necessarily have polyallergy, a documented, causal relationship between exposure to 2 or more specific, sensitizing allergens and the subsequent occurrence of relevant clinical symptoms of allergy. Allergen immunotherapy treatment strategy for the polysensitized patient in Europe is to treat the single or 2 most clinically relevant allergen(s), whereas patients in the United States are usually treated for all potential clinically relevant allergens.Copyright © 2017 Elsevier Inc. All rights reserved.

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