• Rev Assoc Med Bras (1992) · Jan 2021

    Possible role of exogenous melatonin in preventing more serious COVID-19 infection in patients with type 2 diabetes mellitus.

    • Wagner José Martorina and Almir Tavares.
    • Universidade Federal de Minas Gerais, Postgraduate Program in Neurosciences - Belo Horizonte, Brazil.
    • Rev Assoc Med Bras (1992). 2021 Jan 1; 67Suppl 1 (Suppl 1): 18-21.

    AbstractCOVID-19 infection is more severe in patients with type 2 diabetes mellitus (DM2). The severity of this viral infection is associated with an intense inflammatory activity. DM2 is a disease that also determines a greater degree of systemic inflammation. This is due to hyperglycemia, the higher prevalence of sleep disorders and also the low levels of melatonin, a substance with anti-inflammatory actions, in these patients. In this article, we suggest that exogenous melatonin may have an important anti-inflammatory role in preventing severe forms of COVID -19 in patients with DM2.

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