• Rev Assoc Med Bras (1992) · Feb 2021

    Abdominal drain amylase on the first day after pancreatectomy: a predictive factor for pancreatic fistula.

    • Pablo Henrique Brito da Rosa, Adriana Sañudo, Edson José Lobo, Alberto Goldenberg, Gaspar de Jesus Lopes Filho, and Franz Robert Apodaca Torrez.
    • Universidade Federal de São Paulo, Department of Surgery - São Paulo (SP), Brazil.
    • Rev Assoc Med Bras (1992). 2021 Feb 1; 67 (2): 292-296.

    ObjectiveTo analyze abdominal drain on the first postoperative day and evaluate its predictive nature for the diagnosis of Pancreatic Fistula exclusion, seeking to establish a cutoff point from which lower values demonstrate safety in excluding the possibility of this complication.MethodsFrom August 2017 to June 2020, data from 48 patients undergoing pancreatic resection were collected and analyzed from a prospective cohort. The patients were divided into two groups, one group consisting of patients who did not develop PF (Group A), and the other composed of patients who developed PF (Group B). The receiver operation characteristic curve was constructed, and cutoff points were evaluated by calculating sensitivity and specificity.ResultsGroup A brought 30 patients together (62.5%) and Group B brought 18 patients together (37.5%). The 444 U/L value was the most satisfactory cutoff point for the receiver operation characteristic curve (CI 0.690-0.941), with a sensitivity of 94.4% and a specificity of 60%, thus being able to select 18 of 30 patients who did not succumb to PF.ConclusionsAbdominal drain on the first postoperative day can be used as a predictive factor in the diagnosis of PF exclusion (CI 0.690-0.941), with the value of 444 U/L being the best performance cutoff point.

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