• Weizhao Huang, Zhou Cheng, Xiaozu Liao, Liqiang Wang, Junlin Wen, Jianwei Li, Haiming Jiang, Yong Yuan, and Binfei Li.
• Department of Cardiothoracic Surgery, Zhongshan People's Hospital (Zhongshan Hospital of Sun Yat-Sen University) China.
• Medicine (Baltimore). 2021 Jul 30; 100 (30): e26798e26798.

IntroductionPatients with coronavirus disease (COVID-19) may develop acute respiratory distress syndrome (ARDS). There have been few reports of postpartum woman with ARDS secondary to COVID-19 who required respiratory support using veno-venous extracorporeal membrane oxygenation (ECMO). We present the case of a 31-year-old woman who was admitted to hospital at 35 weeks gestation with ARDS secondary to COVID-19 and required ECMO during the postpartum period.Patient ConcernsThe patient had obvious dyspnea, accompanied by chills and fever. Her dyspnea worsened and her arterial oxygen saturation decreased rapidly.DiagnosisARDS secondary to COVID-19.InterventionsEmergency bedside cesarean section. Medications included immunotherapy (thymosin α 1), antivirals (lopinavir/ritonavir and ribavirin), antibiotics (imipenem-cilastatin sodium and vancomycin), and methylprednisolone. Ventilatory support was provided using invasive mechanical ventilation. This was replaced by venous-venous ECMO 5 days postpartum. ECMO management focused on blood volume control, coagulation function adjustment, and airway management.OutcomesThe patient was successfully weaned for ECMO and the ventilator and made a good recovery.ConclusionSpecial care, including blood volume control, coagulation function adjustment, and airway management, should be provided to postpartum patients with ARDS secondary to COVID-19 who require ECMO support.Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.

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