• Medicine · Aug 2021

    Case Reports

    Primary signet ring cell carcinoma of the uterine cervix: A case report.

    • Yeon Hee Kim, Su Jeong Lee, Seon Ui Lee, In Sun Hwang, Kwang Il Yim, and Jin Hwi Kim.
    • Department of Obstetrics and Gynecology, Uijeongbu St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Uijeongbu-si, Gyeonggi-do, Korea.
    • Medicine (Baltimore). 2021 Aug 6; 100 (31): e26844e26844.

    RationalePrimary signet ring cell carcinoma of the uterine cervix is extremely rare and the clinical characteristics and prognosis are not well known and there are no specific guidelines for treatment.Patient ConcernsA 43-year-old woman was referred to our hospital for abnormal uterine bleeding lasting 1 month.DiagnosesHistological examination revealed a signet ring cell carcinoma of the uterine cervix. After evaluation of extragenital origin, the patient was diagnosed International Federation of Gynecology and Obstetrics stage IIIC1 primary signet ring cell carcinoma or the uterine cervix.InterventionThe patient was prescribed concomitant chemo-radiation followed by intracavitary brachytherapy.OutcomesShe showed no evidence of disease after treatment but, it recurred after 7 months of last treatment.LessonsDifferent approaches to diagnosis and treatment of this rare disease are needed and molecular pathological studies related to the onset of the disease are required.Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.

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