• Yuan-Yuan Liu, Ling-Yun Shi, Yong-Mei Duan, and Xiu-Mei Li.
• Department of Operating Room Disinfection Supply Center, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China.
• Medicine (Baltimore). 2021 Aug 13; 100 (32): e26814e26814.

BackgroundThe presence of biological particles in the air inside operating theatres has the potential to cause severe surgical site infections. Recently, laminar airflow systems have been regarded as a means to reducing surgical site infections using airborne microbes. Still, other publications have argued the benefits of laminar airflow systems, stating the likelihood of adverse effects. Therefore, we will conduct this systematic study to evaluate the applicational value of adopting laminar airflow systems in operating theatres to minimize surgical site infections.MethodsReporting of this study adheres to the guidelines of Preferred Reporting Items for Systematic Review and Meta-analysis Protocols. The authors will perform a systematic search on MEDLINE, Web of Science, EMBASE, the China national knowledge infrastructure, and the Cochrane Library from their commencement until June 2021. The search will identify relevant randomized and non-randomized controlled trials that evaluates the applicational value of using laminar airflow ventilation in surgical theatres to minimize surgical site infections. There are no restrictions on language. Two authors will independently screen the identified studies, perform data extraction, and use an appropriate method to evaluate the bias risk in the included studies.ResultsThe work done in the present study will enhance the existing literature on the applicational value of laminar airflow ventilation in surgical theatre to reduce surgical site infections.ConclusionThe outcomes are a reference for healthcare practitioners and patients when making informed decisions regarding care during surgeries.Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.

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