• Rheum. Dis. Clin. North Am. · May 2008

    Topical agents in the treatment of rheumatic pain.

    • R Andrew Moore, Sheena Derry, and Henry J McQuay.
    • Nuffield Department of Anaesthetics, University of Oxford, John Radcliffe Hospital, The Churchill, Headington, Oxford OX3 9DU, UK.
    • Rheum. Dis. Clin. North Am. 2008 May 1;34(2):415-32.

    AbstractIn rheumatic pain there is good evidence that topical nonsteroidal anti-inflammatory drugs are about as effective as oral nonsteroidal anti-inflammatory drugs, but are probably safer and more tolerable because of much less systemic absorption and lower plasma concentrations. The best information is for topical diclofenac. For topical capsaicin, evidence of efficacy is trivial. For topical rubefacients there is no evidence of efficacy.

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