• B M Majstorović, R B Radulović, D A Kastratović, V B Djukić, N P Popović, S Stosić-Divljak, and M M Gajić.
• Odeljenje Instituta za anesteziju i reanimatologiju u Institutu za ORL i MFH KCS, Beograd.
• Acta Chir Iugosl. 2008 Jan 1;55(1):93-7.

AbstractHemodynamic effect of different techniques and type of anesthesia are defined. The volume of reduced hemorrhage in surgical field is debatable, without any definite conclusion. The objective of the study is to investigate the effects of local infiltrative anesthesia with adrenaline during general balanced anesthesia and nitroglicerol on blood presure and hemorrhage reduction in middle ear operations. Prospective, randomized study included 58 adult patients planned for the otorhinolaryngological surgery. Studied group of patient (n 30) planned for middle ear operations. Befora incision surgeon was administered local infiltrative anesthesia using 2% lidocaine with adrenaline (1:200,000) The controls group (n 28), planned for other surgery had no local infiltrative anesthesia with adrenaline. Hemodinamic parameters were monitored before surgical incision and 30 minutes after that. Surgeon's verbal reply on hemorrhage reduction during surgery was recorded. Statistical analysis of parametric data was carried out by Mann-Whitney sum test. Blood pressure and heart rate was not different between the two groups. But, intraoperatively, the study showed lowering of sistolic and diastolic blood pressure. This mode of treatment and surgeon's verbal reply confirmed that local infiltrative anesthesia with adrenaline under balanced anesthesia had no effect on hemorrhage reductionin surgical field.

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