• Ilker Uçkay, Karim Gariani, Victor Dubois-Ferrière, Domizio Suvà, and Benjamin A Lipsky.
• aService of Infectious Diseases bOrthopedic Surgery Service cService of Diabetology and Endocrinology, Geneva University Hospitals and Faculty of Medicine, University of Geneva, Switzerland dDivision of Medical Sciences, University of Oxford, Oxford, UK.
• Curr. Opin. Infect. Dis. 2016 Apr 1; 29 (2): 145-52.

Purpose Of ReviewDiabetes mellitus has reached pandemic levels and will continue to increase worldwide. Physicians and surgeons should know to manage one of its most prevalent complications, the diabetic foot infection (DFI), in a scientifically based and resource-sparing way. We performed a nonsystematic review of recent scientific literature to provide guidance on management of DFIs.Recent FindingsStudies in the past couple of years provide data on which recommendations for diagnosing and treating DFI are based, especially with validated guidelines and reviews of the microbiology and selected aspects of the complex DFI problem. Recent literature provides approaches to prevention and studies support more conservative surgical treatment. Unfortunately, there have been virtually no new therapeutic molecules, antibiotic regimens, randomized trials, or surgical techniques introduced in the recent past; we briefly discuss how this may change in the future.SummaryRecent scientific evidence on DFI strongly supports the value of multidisciplinary and some new care models, guideline-based management, more preventive approaches, and confirms several established therapeutic concepts. In contrast, there has been almost no new substantial information regarding the optimal antibiotic or surgical management in recent literature.

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