• Internal medicine journal · Aug 2021

    Case Reports

    Hyponatraemia due to the syndrome of inappropriate antidiuretic hormone secretion in adults with respiratory syncytial virus infection.

    • Matthew Smale, Julia Freckelton, Mary Waters, and Vivian Grill.
    • Department of General Medicine, St Vincent's Hospital Melbourne, Melbourne, Victoria, Australia.
    • Intern Med J. 2021 Aug 1; 51 (8): 1340-1343.

    AbstractWe present a case of severe hyponatraemia due to syndrome of inappropriate antidiuretic hormone (SIADH) in a patient with respiratory syncytial virus (RSV) infection. A retrospective analysis of all patients admitted to our hospital with RSV in the preceding 3-year period revealed hyponatraemia in 41 (28%) cases, of which 13 (8.9%) were moderate or severe. SIADH was explored and confirmed in five (3.4%) patients, raising this as an important, previously unrecognised, complication of RSV infection in adults. Physician awareness of SIADH as a potential complication of RSV will facilitate early diagnosis and treatment of this potentially fatal disorder.© 2021 Royal Australasian College of Physicians.

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