• Yuankai Huo, Ruining Deng, Quan Liu, Agnes B Fogo, and Haichun Yang.
• Department of Electrical Engineering and Computer Science, Vanderbilt University, Nashville, Tennessee, USA.
• Kidney Int. 2021 Jun 1; 99 (6): 1309-1320.

AbstractThe explosive growth of artificial intelligence (AI) technologies, especially deep learning methods, has been translated at revolutionary speed to efforts in AI-assisted healthcare. New applications of AI to renal pathology have recently become available, driven by the successful AI deployments in digital pathology. However, synergetic developments of renal pathology and AI require close interdisciplinary collaborations between computer scientists and renal pathologists. Computer scientists should understand that not every AI innovation is translatable to renal pathology, while renal pathologists should capture high-level principles of the relevant AI technologies. Herein, we provide an integrated review on current and possible future applications in AI-assisted renal pathology, by including perspectives from computer scientists and renal pathologists. First, the standard stages, from data collection to analysis, in full-stack AI-assisted renal pathology studies are reviewed. Second, representative renal pathology-optimized AI techniques are introduced. Last, we review current clinical AI applications, as well as promising future applications with the recent advances in AI.Copyright © 2021 International Society of Nephrology. Published by Elsevier Inc. All rights reserved.

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