• Magn Reson Med · Oct 1992

    In vivo identification and monitoring of changes in rat brain glucose by two-dimensional shift-correlated 1H NMR spectroscopy.

    • M Peres, O Fedeli, B Barrere, B Gillet, G Berenger, J Seylaz, and J C Beloeil.
    • Institut de Chimie des Substances Naturelles C.N.R.S., Gif sur Yvette, France.
    • Magn Reson Med. 1992 Oct 1; 27 (2): 356-61.

    AbstractIntracerebral glucose resonance was directly detected and resolved in vivo by two-dimensional shift-correlated (COSY) 1H NMR spectroscopy in anesthetized rats (n = 4). The relative changes in brain glucose concentration were measured by volume integration of the alpha-D-glucose cross peak in the 2D COSY spectra. This report demonstrates the possibility of monitoring the variations in cerebral glucose following iv injection of glucose.

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