• Respirology · Sep 2007

    Case Reports

    Cyclophosphamide-induced acute respiratory distress syndrome.

    • Jorge Brieva.
    • Intensive Care Unit, Mater Misericordiae Hospital, Newcastle, New South Wales, Australia. jorge.brieva@mater.health.nsw.gov.au
    • Respirology. 2007 Sep 1; 12 (5): 769-73.

    AbstractCyclophosphamide is widely used in neoplastic and inflammatory diseases. Although several adverse events have been described with its use, acute and subacute interstitial pneumonitis leading to pulmonary fibrosis is rare and potentially fatal. This case report describes a 64-year-old man who, after the fifth chemotherapy cycle, developed a severe ARDS leading to pulmonary fibrosis in just 30 days.

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