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- C Braun, P Duffau, F-X Mahon, E Rosier, T Leguay, G Etienne, and M Michaud.
- Service de médecine interne et maladies infectieuses, hôpital Haut-Lévêque, avenue de Magellan, 33604 Pessac cedex, France. carine.braun@laposte.net
- Rev Med Interne. 2007 Feb 1; 28 (2): 116-9.
IntroductionHypercalcemia frequently occurs in the course of Adult T-cell leukemia/lymphoma (ATLL). We report the first case of acute pancreatitis revealing ATLL.ExegesisA 41-year-old woman, without medical history, presented with acute pancreatitis. Physical examination found recent loss of weight, hepatosplenomegaly and generalised lymphoadenopathy. Biochemical tests showed severe hypercalcemia and the peripheral white blood cell count revealed an atypical lymphocytosis. ATLL was diagnosed by immunophenotypic and morphological analysis of circulating lymphocytes, bone marrow and lymphatic node biopsy. Level of serum parathyroid hormone-related protein was not increased. We discuss the mechanism of hypercalcemia in this context.ConclusionIn spite of the high prevalence of hypercalcemia in ATLL, acute pancreatitis revealing this pathology is an exceptional condition.
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