• Nan Fang Yi Ke Da Xue Xue Bao · Dec 2008

    [Color Doppler and contrast-enhanced ultrasonography for assessment of vascular perfusion in porcine liver allografts with acute graft rejection].

    • Qian Wang, Wei-bing Gong, Jin-ming Xie, Yu Sun, and Ying Yuan.
    • Department of Ultrasound, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
    • Nan Fang Yi Ke Da Xue Xue Bao. 2008 Dec 1;28(12):2251-2.

    ObjectiveTo investigate the feasibility of evaluating hepatic blood perfusion after liver transplantation using color Doppler and contrast-enhanced ultrasonography and the diagnostic value of hepatic blood perfusion for acute graft rejection.MethodIn this before-after study with quantitative analysis, contrast-enhanced sonography was performed with simultaneous liver function monitoring in porcine models of allograft liver transplantation before and after the operation.ResultsIn pigs with acute graft rejection, the AUC decreased significantly after transplantation as compared with that of non-rejection transplant group (F=11.069, P=0.011), but the parameters including A, Alpha, C, t(0), DPI, or TTP showed no significant differences between the two groups.ConclusionsPulse-inversion contrast harmonic imaging combined with acoustic quantitative technology can be an efficient means for evaluating blood perfusion in the liver allograft, and the TIC obtained using this method possesses high values for quantitative evaluation of liver allograft rejection.

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