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- Vu Dinh Thiem, Jacqueline L Deen, Lorenz von Seidlein, Do Gia Canh, Dang Duc Anh, Jin-Kyung Park, Mohammad Ali, M Carolina Danovaro-Holliday, Nguyen Dinh Son, Nguyen Thai Hoa, Jan Holmgren, and John D Clemens.
- National Institute of Hygiene and Epidemiology, Hanoi, Vietnam.
- Vaccine. 2006 May 15; 24 (20): 4297-303.
AbstractWe assessed the long-term protection afforded by a killed whole-cell oral cholera vaccine produced in Vietnam. A mass immunization of children and adults with the killed whole-cell oral cholera vaccine was undertaken in half of the communes of Hue, Vietnam, in 1998; the remaining communes were immunized in 2000. No cholera was observed in Hue until 2003, when an outbreak of El Tor cholera made it possible to conduct a case-control study. The overall vaccine effectiveness 3-5 years after vaccination was 50% (9-63%). This low-cost, easily administered vaccine should be considered as a tool for the control of cholera.
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