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Randomized Controlled Trial Comparative Study
A randomised comparison of lidocaine 2% gel and proparacaine 0.5% eye drops in paediatric squint surgery.
- R Saxena, R Sinha, Chandralekha, M Batra, and V K Mohan.
- Department of Anaesthesiology, All India Institute of Medical Sciences, New Delhi, India.
- Anaesthesia. 2013 Jul 1;68(7):747-52.
AbstractWe conducted a randomised trial comparing lidocaine 2% gel with proparacaine 0.5% eye drops in children having elective squint surgery. One hundred and forty children aged between 3 and 14 years were recruited. The requirement for intra-operative fentanyl and postoperative ibuprofen was significantly less in the lidocaine group compared with the proparacaine group (1 (1.7%) vs 12 (18.5%), p=0.002 and 16 (27.6%) 38 (58.5%), p=0.001, respectively). The incidence of postoperative nausea and vomiting was significantly less in the lidocaine group compared with the proparacaine group (6 (10.3%) vs 16 (24.6%), p=0.04). There were no differences between the groups in terms of incidence and severity of the oculocardiac reflex. We conclude that, compared with proparacaine 0.5% eye drops, a single application of lidocaine 2% gel improves peri-operative analgesia and reduces the incidence of postoperative nausea and vomiting in elective paediatric squint surgery.Anaesthesia © 2013 The Association of Anaesthetists of Great Britain and Ireland.
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