• André Luiz Jardini, Maria Aparecida Larosa, Rubens Maciel Filho, Cecília Amélia de Carvalho Zavaglia, Luis Fernando Bernardes, Carlos Salles Lambert, Davi Reis Calderoni, and Paulo Kharmandayan.
• National Institute of Biofabrication (INCT-BIOFABRIS), Campinas, Brazil; School of Chemical Engineering, State University of Campinas, Campinas, Brazil.
• J Craniomaxillofac Surg. 2014 Dec 1; 42 (8): 1877-84.

AbstractAdditive manufacturing (AM) technology from engineering has helped to achieve several advances in the medical field, particularly as far as fabrication of implants is concerned. The use of AM has made it possible to carry out surgical planning and simulation using a three-dimensional physical model which accurately represents the patient's anatomy. AM technology enables the production of models and implants directly from a 3D virtual model, facilitating surgical procedures and reducing risks. Furthermore, AM has been used to produce implants designed for individual patients in areas of medicine such as craniomaxillofacial surgery, with optimal size, shape and mechanical properties. This work presents AM technologies which were applied to design and fabricate a biomodel and customized implant for the surgical reconstruction of a large cranial defect. A series of computed tomography data was obtained and software was used to extract the cranial geometry. The protocol presented was used to create an anatomic biomodel of the bone defect for surgical planning and, finally, the design and manufacture of the patient-specific implant. Copyright © 2014 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.

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