• Graefes Arch. Clin. Exp. Ophthalmol. · Jul 2001

    Case Reports

    Orbital presentations of giant cell arteritis.

    • A G Lee, R A Tang, S E Feldon, M Pless, J S Schiffman, R M Rubin, and N Rao.
    • Department of Ophthalmology, University of Iowa Hospitals and Clinics, Iowa City 52242, USA. Andrew-lee@uiowa.edu
    • Graefes Arch. Clin. Exp. Ophthalmol. 2001 Jul 1;239(7):509-13.

    Backgroundgiant cell arteritis (GCA) is a systemic vasculitis that may affect the optic nerve and cause blindness (e.g. ischemic optic neuropathy). Orbital inflammatory disease, however, is an uncommon presentation of GCA.Purposeto alert clinicians to the orbital presentations of GCA.Patients And Methodsa retrospective case series from tertiary care academic ophthalmic referral centers of four patients with orbital manifestations of giant cell arteritis.Resultspresentation of cases and review of the literature. In three cases, a temporal artery biopsy was diagnostic of GCA, but in one case, an orbital biopsy was needed to confirm the diagnosis.ConclusionGCA can have orbital manifestations and clinicians should be aware of this unusual presentation of GCA in cases of presumed orbital inflammatory pseudotumor in the elderly.

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