• Robin Brünn, Beate S Müller, Benno Flaig, Petra Kellermann-Mühlhoff, Ute Karbach, Sara Söling, Christiane Muth, Marjan van den Akker, and AdAM Study consortium.
• Institute of General Practice, Goethe University, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany. bruenn@allgemeinmedizin.uni-frankfurt.de.
• Bmc Fam Pract. 2021 Aug 21; 22 (1): 168.

BackgroundTo investigate patients' perspectives on polypharmacy and the use of a digital decision support system to assist general practitioners (GPs) in performing medication reviews.MethodsQualitative interviews with patients or informal caregivers recruited from participants in a cluster-randomized controlled clinical trial (cRCT). The interviews were transcribed verbatim and analyzed using thematic analysis.ResultsWe conducted 13 interviews and identified the following seven themes: the patients successfully integrated medication use in their everyday lives, used medication plans, had both good and bad personal experiences with their drugs, regarded their healthcare providers as the main source of medication-related information, discussed medication changes with their GPs, had trusting relationships with them, and viewed the use of digital decision support tools for medication reviews positively. No unwanted adverse effects were reported.ConclusionsDespite drug-related problems, patients appeared to cope well with their medications. They also trusted their GPs, despite acknowledging polypharmacy to be a complex field for them. The use of a digital support system was appreciated and linked to the hope that reasons for selecting specific medication regimens would become more comprehensible. Further research with a more diverse sampling might add more patient perspectives.Trial RegistrationClinicalTrials.gov, NCT03430336 . Registered on February 6, 2018.© 2021. The Author(s).

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