• E W Johnson.
• Department of Physical Medicine, Ohio State University, Columbus 43210.
• Muscle Nerve. 1993 Feb 1; 16 (2): 127-34.

AbstractA MEDLINE review suggested a lack of recent studies about the entrapments seen with underlying diabetic neuropathy. Suggested protocols for research in diabetic peripheral neuropathy have not included the concepts of entrapments as an early--indeed, first manifestation of the neuropathy. Carpal tunnel syndrome is a frequent accompaniment of diabetic peripheral neuropathy. Assessment of the degree of entrapment superimposed on the generalized peripheral neuropathy can be clarified by analysis of the CMAP and the SNAP--particularly with respect to duration of the negative spike of the action potential. Also, analysis of the action potentials elicited by stimulation of the ulnar and radial nerves and their comparison with the median nerve is often helpful. Finally careful inspection of the action potential when stimulating proximal and distal to the entrapment will establish the degree of nerve compromise relative to the underlying diabetic neuropathy.

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