• Chihiro Nogami, Keisuke Hanada, Kayoko Yokoi, Tatsuya Nakanowatari, Kosuke Tasa, Kazutaka Sakamoto, Yuki Saito, Sunao Takemura, and Kazumi Hirayama.
• Department of Rehabilitation, Yamagata Saisei Hospital, Japan.
• Intern. Med. 2022 Feb 15; 61 (4): 541-546.

AbstractNo study has reported a unilateral localized cerebral lesion of the posterior insula bilaterally reducing noxious stimuli perception. A 57-year-old man with an infarct involving the right posterior insula presented with reduced somatosensory response in the upper and lower left extremities. Furthermore, there was a reduced response to noxious stimulation in the right upper and lower limbs. We noted reductions in pain, noxious heat and cold perceptions, and sensitivity to increasing temperature. Other somatic sensations, including non-noxious temperatures, remained intact in the right upper and lower extremities. These findings in our patient with a unilateral insular lesion indicated a bilaterally reduced perception of noxious stimulation.

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