• Internal medicine · Nov 2021

    Case Reports

    Cranial Nerve Involvement and Dysautonomia in Post-COVID-19 Guillain-Barré Syndrome.

    • Toshiyuki Kakumoto, Satoshi Kobayashi, Hayato Yuuki, Mitsuhiro Kainaga, Yuichiro Shirota, Masashi Hamada, Hashimoto MaedaMeikoMDepartment of Neurology, Graduate School of Medicine, The University of Tokyo, Japan., Akatsuki Kubota, Mizuho Kawai, Masaaki Saito, Hiroyuki Ishiura, and Tatsushi Toda.
    • Department of Neurology, Graduate School of Medicine, The University of Tokyo, Japan.
    • Intern. Med. 2021 Nov 1; 60 (21): 3477-3480.

    AbstractThe clinical characteristics of Guillain-Barré syndrome (GBS) after coronavirus disease 2019 (COVID-19) remain unclear due to the small number of cases. We herein report a case of a Japanese patient with post-COVID-19 GBS who presented with facial and limb muscle weakness, sensory deficits, and autonomic dysfunction. Nerve conduction studies revealed demyelination. Head magnetic resonance imaging showed contrast enhancement in the bilateral facial nerves. Systemic management, including intubation, intravenous immunoglobulin therapy, and rehabilitation, improved the patient's condition. This was the first Japanese case of acute inflammatory demyelinating polyneuropathy after COVID-19 and was characterized by autonomic dysfunction and facial nerve enhancement.

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