• E Egeli, U Harputluoglu, F Oghan, Y Demiraran, E Guclu, and O Ozturk.
• University of Abant Izzet Baysal, Düzce Faculty of Medicine, Department of Otorhinolaryngology-Head and Neck Surgery, Düzce, Turkey.
• Int. J. Pediatr. Otorhinolaryngol. 2005 Jun 1; 69 (6): 811-5.

ObjectiveTo evaluate the efficacy of lidocaine with adrenaline on post-operative morbidity in pediatric patients after tonsillectomy.Study DesignA double blind prospective randomized controlled clinical study.MethodsThe study is consisting of two groups of pediatric patients following tonsillectomy performed in a university hospital. One group received lidocaine with adrenaline soaked swabs packed in their tonsillar fossae while the control group received saline-soaked swabs. Chi-square and two-tailed unpaired Student's t-tests were used to compare the two independent groups. p<0.05 was accepted as statistically significant.ResultsNo significant pain-relieving effect was seen in the lidocaine with adrenaline group (p>0.05) and also the other post-operative parameters such as nausea, fever, vomiting, odor, bleeding, otalgia and trismus were not statistically different between the two groups based on chi-square analysis (p>0.05). There were no complications associated with lidocaine and adrenaline.ConclusionWe suggest that application of topical lidocaine with adrenaline seems to be a safe and easy medication for local anesthetic use. However, in our study, lidocaine with adrenaline offered no advantage over placebo in the control of post-operative pain and other morbidity related factors following pediatric tonsillectomy. We therefore do not recommend topical application of lidocaine with adrenaline for reducing morbidity in pediatric tonsil surgery.

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